Regenerative Eye Therapies
Personalized Eye Drop Therapies Prepared from Your Own Blood.
For patients experiencing chronic dry eye, ocular surface disease, or delayed corneal healing, personalized blood-derived eye drops may offer support beyond traditional artificial tears.
Table of Contents
At Central Ohio Compounding Pharmacy, we prepare three types of eye drop therapies in our sterile compounding lab. Each therapy is derived from your own blood but differs in processing methods, concentration of healing factors, and therapeutic goals.
Depending on the therapy prescribed, blood collection may take place either at our pharmacy or through one of our trusted laboratory partners before your customized eye drops are prepared.
Understanding Your Options
| Therapy | Primary Focus | Common Uses |
|---|---|---|
| Autologous Serum Tears (AST) | Mimics natural tears and supports ocular surface health | Dry eye disease and ocular surface disorders |
| Platelet-Rich Plasma (PRP) Eye Drops | Enhanced regenerative support through concentrated platelets and growth factors | More significant ocular surface disease and healing needs |
| Endoret® PRGF® | Advanced regenerative therapy utilizing a standardized preparation process | Complex ocular surface disease and advanced healing support |
Your eye care provider will determine which therapy is most appropriate for your condition.
Autologous Serum Tears (AST)
A Personalized Approach to Ocular Surface Support
Autologous Serum Tears are often considered the first step beyond traditional dry eye treatments. Prepared from your own blood, these customized eye drops contain many of the same proteins, vitamins, growth factors, and nutrients naturally found in healthy tears.
Unlike artificial tears, which primarily provide lubrication, serum tears help nourish and support the ocular surface with naturally occurring components that more closely resemble your natural tear film.
Benefits of Autologous Serum Tears
- Contains many components naturally found in healthy tears
- Helps nourish and support the ocular surface
- Preservative-free
- Personalized from your own blood
- May improve comfort, lubrication, and tear film stability
Common Uses
- Moderate to severe dry eye disease
- Ocular surface disease
- Neurotrophic keratopathy
- Corneal surface damage
- Recovery following LASIK, PRK, or other ocular procedures
What Makes AST Different?
Autologous Serum Tears offer a personalized treatment option for patients whose symptoms persist despite traditional therapies. Because they contain naturally occurring tear components not found in artificial tears, they may provide additional support for ocular surface health and healing.
Platelet-Rich Plasma (PRP) Eye Drops
Enhanced Regenerative Support
PRP Eye Drops build upon the foundation of serum tears by concentrating platelets within the plasma. These platelets contain naturally occurring growth factors involved in tissue repair, healing, and regeneration.
For patients with more significant ocular surface disease or delayed healing, PRP may provide additional regenerative support beyond traditional serum tears.
Benefits of PRP Eye Drops
- Rich in naturally occurring growth factors
- Supports tissue repair and regeneration
- May promote corneal healing
- Preservative-free
- Personalized from your own blood
- Designed to support recovery of the ocular surface
Common Uses
- Chronic dry eye disease
- Persistent epithelial defects
- Corneal ulcers
- Neurotrophic keratitis
- Ocular surface disease
- Recovery following ocular surgery
What Makes PRP Different?
Compared with serum tears, PRP contains a higher concentration of platelets and growth factors. These healing factors may help support tissue repair and recovery in patients requiring enhanced regenerative support.
Endoret® PRGF®
Next-Generation Regenerative Eye Therapy
For patients experiencing chronic dry eye, persistent ocular surface disease, delayed corneal healing, or complex corneal conditions, Endoret® PRGF® offers an advanced regenerative treatment approach designed to support the eye’s natural healing process.
Using a small sample of your own blood, Endoret® PRGF® (Plasma Rich in Growth Factors) is prepared through a proprietary, standardized process that isolates and concentrates beneficial growth factors while minimizing inflammatory components.
Unlike traditional lubricating eye drops, Endoret® PRGF® is designed to actively support tissue repair, regeneration, and recovery of the ocular surface.
Benefits of Endoret® PRGF®
- Supports the eye’s natural healing process
- Rich in naturally occurring growth factors
- Leukocyte-free formulation designed to minimize inflammatory components
- Supports corneal repair and regeneration
- May improve comfort and quality of life
- Personalized from your own blood
- Prepared using a standardized processing protocol
Common Uses
- Severe dry eye disease
- Persistent epithelial defects
- Corneal ulcers
- Neurotrophic corneal conditions
- Ocular burns
- Recovery following ocular surgery
What Makes PRGF Different?
While all three therapies are derived from your own blood, Endoret® PRGF® utilizes a highly innovative preparation process developed specifically for regenerative medicine applications.
The Endoret® technology is designed to optimize beneficial growth factors while minimizing inflammatory components, resulting in a leukocyte-free formulation intended to support healing and tissue regeneration.
Convenient In-House Blood Collection
Unlike other blood-derived eye drop therapies that may require a separate laboratory visit, Endoret® PRGF® patients can complete their blood draw directly at Central Ohio Compounding Pharmacy.
This streamlined process allows our team to coordinate blood collection, preparation, and dispensing while providing a convenient experience for patients.
Key Differentiators
- Proprietary Endoret® PRGF® technology
- Growth factor-rich formulation
- Leukocyte-free design
- Extensive use in regenerative medicine and ophthalmology
- Developed through decades of research and clinical experience
- Convenient in-house blood collection and coordination
Backed by Research
Endoret® PRGF® was developed by BTI Biotechnology Institute, a global leader in regenerative medicine with more than 25 years of research and innovation. The technology has been studied extensively in ophthalmology and regenerative medicine and continues to be utilized worldwide.
Research involving patients with ocular surface disease has demonstrated improvements in corneal health and patient-reported symptoms. In a multicenter study involving 153 patients, researchers reported significant improvements in corneal staining outcomes along with meaningful reductions in ocular discomfort.
How the Process Works
Personalized Care Every Step of the Way
Each therapy begins with a blood draw and is prepared specifically for you. While the collection process varies by treatment, our team works closely with your prescribing provider to coordinate preparation and dispensing of your personalized eye drops.
Autologous Serum Tears & PRP Eye Drops
Step 1: Blood Collection
A blood sample is collected at our trusted laboratory partner, ARCpoint Labs.
Step 2: Processing
The sample is processed according to the prescribed therapy.
Step 3: Sterile Preparation
Your personalized eye drops are prepared in our sterile compounding laboratory.
Step 4: Treatment Begins
You’ll receive instructions regarding storage, handling, and administration.
Endoret® PRGF®
Step 1: Blood Collection at Central Ohio Compounding Pharmacy
A small sample of blood is drawn by our trained team.
Step 2: Specialized Processing
The sample is prepared using the Endoret® PRGF® process to isolate growth factor-rich plasma while minimizing inflammatory components.
Step 3: Sterile Preparation
Your personalized eye drops are prepared in our sterile compounding laboratory.
Step 4: Treatment Begins
You’ll receive instructions regarding storage, handling, and administration.
Most preparations are completed within the same day, though timing may vary.
Why Choose Central Ohio Compounding Pharmacy?
Expertise in Personalized Ophthalmic Care
Central Ohio Compounding Pharmacy works closely with eye care providers to prepare customized therapies designed to support ocular surface health and healing.
- Sterile compounding performed in our laboratory
- Personalized therapies prepared from your own blood
- Convenient coordination with trusted laboratory partners when needed
- In-house blood collection available for Endoret® PRGF® patients
- Experienced compounding team dedicated to ophthalmic therapies
- Collaborative care with your prescribing eye care provider
- Serving patients throughout Central Ohio and beyond
Ready to Learn More?
Whether you’re exploring Autologous Serum Tears, PRP Eye Drops, or Endoret® PRGF®, our team is here to help.
For questions about any of these therapies, contact us at 614-569-4799.
Interested in Endoret® PRGF®?
Schedule your PRGF blood draw appointment below.