Non-sterile compounding is the preparation of medications in environments that do not require sterility but adhere to stringent safety and quality standards. This form of compounding is used for medications that are administered orally, topically, or through other non-injectable routes.

What is Non-Sterile Compounding?

Unlike sterile compounding, which is used for injectable medications or those that enter sterile areas of the body, non-sterile compounding focuses on medications applied or taken through non-sterile routes.

Key Characteristics

• Customization: Tailoring the strength, dosage form, or ingredients of a medication.
• Flexibility: Preparing medications in forms not commercially available.
• Adaptability: Creating formulations for patients with allergies or sensitivities to certain ingredients.

Compounding pharmacists work closely with providers to ensure that the medications align with the patient’s unique needs, enhancing the overall care experience.

Common Examples

Non-sterile preparations are designed to address the specific medical and practical needs of both patients and providers.

Oral Medications

• Capsules: Customized to include the precise dosage required by the patient, especially for medications not available commercially.
• Flavored Suspensions: Liquid forms of medication with added flavors to improve palatability, especially for children or pets.
• Powders: Convenient options for patients who require dissolvable medications.

Topical Medications

• Creams and Ointments: Used for conditions like eczema, psoriasis, or localized pain.
• Gels: Prepared for conditions requiring localized absorption, such as hormonal therapies or anti-inflammatory applications.
• Lotions: Ideal for broader skin application and conditions requiring hydration or active ingredients.

Sublingual Medications

Sublingual forms dissolve under the tongue and are absorbed directly into the bloodstream.

• Troches: Custom-dosed lozenges designed for medications requiring rapid absorption.
• Dissolvable Tablets: An alternative for patients who have difficulty swallowing pills.

Suppositories

Suppositories are compounded for patients requiring medication delivery through rectal or vaginal routes.

• Rectal Suppositories: Used for conditions like hemorrhoids, nausea, or pain relief.
• Vaginal Suppositories: Often prepared for infections or hormonal applications.

BHRT

The hormones used in BHRT address different aspects of hormonal health.

• Estrogen (Estradiol and Estriol): Alleviates symptoms of menopause, such as hot flashes and vaginal dryness.
• Progesterone: Essential for balancing estrogen and maintaining uterine health. It also supports sleep and mood regulation.
• Testosterone: Often used in men and women to enhance energy, libido, and muscle strength.
• DHEA (Dehydroepiandrosterone): A precursor to sex hormones, supporting overall hormonal balance.
• Thyroid Hormones (T3 and T4): Addresses metabolic issues related to hypothyroidism.

Each hormone is carefully compounded to match the patient’s specific therapeutic requirements.

Veterinary Compounding

Non-sterile preparations are crucial in veterinary medicine, offering solutions for animals with unique medical needs.

• Flavored Chews: Medications formulated into tasty treats for easier administration.
• Custom Liquid Suspensions: For animals that cannot swallow pills or require specific dosages.

For specific formulations, ask our pharmacists. 

Benefits of Non-sterile Medication

Non-sterile compounding allows pharmacists to address challenges associated with commercially available medications.

Addressing Allergies or Sensitivities

Patients with allergies to dyes, preservatives, or other inactive ingredients in standard medications can benefit from compounded alternatives that eliminate these irritants.

Adjusting Dosages

Compounded medications can be prepared in dosages not commercially available, ensuring that patients receive the precise amount they need.

Improving Compliance

Flavoring or altering the form of medications can make them more palatable or easier to administer, particularly for children, pets, or elderly patients.

Why Choose Central Ohio Compounding Pharmacy

Central Ohio Compounding Pharmacy is dedicated to providing high-quality non-sterile preparations services for patients and providers. By working closely with healthcare professionals, COCPRx ensures that medications are customized to meet the specific needs of each patient, from unique dosages to alternative forms. With a commitment to precision and safety, COCPRx delivers solutions that support better care and compliance. Whether preparing oral medications, topical creams, or veterinary formulations, COCPRx is a trusted resource for personalized pharmacy services.